1-Oleyl-2-hydroxy-sn-glycero-3-PA (sodium salt) (Synonyms: LPA O-18:0; O-18:0 LPA; 1-Octadecyl-2-hydroxy-sn-glycero-3-phosphate; 1-Octadecyl LPA; 1-Octadecyl Lysophosphatidic Acid; 1-Oleyl LPA; 1-Oleyl Lysophosphatidic Acid; PA(O-18:0/0:0)) |
| Catalog No.GC91421 |
1-Oleyl-2-hydroxy-sn-glycero-3-PA (1-Octadecyl LPA) is a LPA analog containing stearyl alcohol at the sn-1 position.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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1-Oleyl-2-hydroxy-sn-glycero-3-PA (1-Octadecyl LPA) is a LPA analog containing stearyl alcohol at the sn-1 position. LPA binds to one of five different G protein-linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.1,2 Alkyl ether-linked LPA derivatives have a higher platelet aggregating activity than the acyl derivatives, most likely stemming from an alkyl-specific LPA receptor. For example, 1-octadecyl LPA has platelet aggregating activity with an EC50 value of 9 nM versus an EC50 value of 177 nM for 1-octadecanoyl LPA.3
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