12(S)-HEPE |
| Catalog No.GC40371 |
12(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 116180-17-7
Sample solution is provided at 25 µL, 10mM.
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12(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO. Unstimulated neutrophils metabolize 12(S)-HEPE to 12(S),20-diHEPE, whereas stimulated neutrophils produce 5(S),12(S)-HEPE via the 5-lipoxygenase pathway. The competitive action of 12(S)-HEPE with arachidonic acid as a substrate for 5-LO in the formation of leukotrienes may provide a basis for the anti-inflammatory potential of ω-3 fatty acids.
Average Rating: 5 (Based on Reviews and 1 reference(s) in Google Scholar.)
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