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14,15-Leukotriene A4 methyl ester (Synonyms: Eoxin A4 methyl ester, EXA4 methyl ester, 14,15-LTA4 methyl ester)

Catalog No.GC41320

14,15-Leukotriene A4 (14,15-LTA4) methyl ester is an esterified form of 14,15-LTA4, a leukotriene isomer formed from arachidonic acid by 15-lipoxygenase (15-LO) that inhibits LTA4 hydrolase.

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14,15-Leukotriene A4 methyl ester Chemical Structure

Cas No.: 75290-58-3

Size Price Stock Qty
25μg
$174.00
In stock
50μg
$332.00
In stock
100μg
$629.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description of 14,15-Leukotriene A4 methyl ester

14,15-Leukotriene A4 (14,15-LTA4) methyl ester is an esterified form of 14,15-LTA4, a leukotriene isomer formed from arachidonic acid by 15-lipoxygenase (15-LO) that inhibits LTA4 hydrolase.

Chemical Properties of 14,15-Leukotriene A4 methyl ester

Cas No. 75290-58-3 SDF
Synonyms Eoxin A4 methyl ester, EXA4 methyl ester, 14,15-LTA4 methyl ester
Canonical SMILES CCCCC[C@H]1[C@@H](O1)/C=C/C=C/C=C\C/C=C\CCCC(OC)=O
Formula C21H32O3 M.Wt 332.5
Solubility Acetone: 30 mg/ml,DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of 14,15-Leukotriene A4 methyl ester

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.0075 mL 15.0376 mL 30.0752 mL
5 mM 0.6015 mL 3.0075 mL 6.015 mL
10 mM 0.3008 mL 1.5038 mL 3.0075 mL
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In vivo Formulation Calculator (Clear solution) of 14,15-Leukotriene A4 methyl ester

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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