6-PPD-quinone |
| Catalog No.GC90761 |
An oxidized derivative of 6-PPD
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2754428-18-5
Sample solution is provided at 25 µL, 10mM.
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6-PPD-quinone is an oxidized derivative of the tire antiozonant and substituted p-phenylenediamine 6-PPD .1 It is toxic to rainbow trout (O. mykiss) and brook trout (S. fontinalis; LC50s = 0.59 and 1.96 µg/L, respectively) but not to arctic char (S. alpinus) and white sturgeon (A. transmontanus; LC50s = >12.7 µg/L for both). 6-PPD-quinone (10 µg/L) induces cell death and germline DNA damage, as well as decreases the number of mitotic cells, in C. elegans gonads.2 Urine levels of 6-PPD-quinone are increased in pregnant women compared to non-pregnant adults and children.3
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