A-834735 |
| Catalog No.GC41481 |
A-834735 is an indole-derived cannabinoid (CB) with a 3-tetramethylcyclopropylmethanone substituent.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 895155-57-4
Sample solution is provided at 25 µL, 10mM.
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A-834735 is an indole-derived cannabinoid (CB) with a 3-tetramethylcyclopropylmethanone substituent. It acts as a full agonist at both the central CB1 and peripheral CB2 receptors in rat with Ki values of 4.6 and 0.31 nM, respectively. and EC50 values of 12 and 0.21 nM, respectively. A-834735 readily crosses the blood-brain barrier, dose-dependently reversing thermal hyperalgesia without adverse side effects in a rat neuropathic pain model.
Average Rating: 5 (Based on Reviews and 28 reference(s) in Google Scholar.)
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