Abacavir hydroxyacetate |
| Catalog No.GC66453 |
Abacavir hydroxyacetate is an orally active inhibitor of IL-20 and PRINS. Abacavir hydroxyacetate reduces proliferation rate of skin in psoriasis as an immune modulator. Abacavir hydroxyacetate can be used for the research of inflammatory skin problems.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1446418-48-9
Sample solution is provided at 25 µL, 10mM.
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Abacavir hydroxyacetate is an orally active inhibitor of IL-20 and PRINS. Abacavir hydroxyacetate reduces proliferation rate of skin in psoriasis as an immune modulator. Abacavir hydroxyacetate can be used for the research of inflammatory skin problems[1][2].
Abacavir hydroxyacetate (10-20 mg/kg; p.o. once) effectively controls psoriasis of mice[2].
| Animal Model: | 6 to 8-week-old male and female SCID mice with implantation of psoriatic tissue[2] |
| Dosage: | 10 and 20 mg/kg |
| Administration: | Oral gavage; 10-20 mg/kg once |
| Result: | Decreased the concentration of PRINS and 1L-20, and reduced the lesion area of skin. Showed a better effect than methotrexate in controlling psoriasis. |
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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