ADBICA N-(4-hydroxypentyl) metabolite (Synonyms: ​ADB-PICA N-(4-hydroxypentyl) metabolite)

ADBICA is a synthetic cannabinoid (CB) that has recently been identified in herbal blends.[1]  Structurally, it is a modified aminoalkylindole like many cannabimimetics with pronounced activity at both CB receptors.[2] ADBICA N-(4-hydroxypentyl) metabolite is a potential phase 1 metabolite of ADBICA, based on the known metabolism of other aminoalkylindoles. The physiological and toxicological properties of this compound have not been determined. This product is intended for forensic and research applications

Reference:
[1]. Uchiyama, N., Matsuda, S., Kawamura, M., et al. Two new-type cannabimimetic quinolinyl carboxylates, QUPIC and QUCHIC, two new cannabimimetic carboxamide derivatives, ADB-FUBINACA and ADBICA, and five synthetic cannabinoids detected with a thiophene derivative α-PVT and an opioid receptor agonist AH-7921 identified in illegal products. Forensic Toxicol. 31(2), 223-240 (2013).
[2]. Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding. Drug Alcohol Depend. 60(2), 133-140 (2000).
[3]. Wintermeyer, A., Möller, I., Thevis, M., et al. In vitro phase I metabolism of the synthetic cannabimimetic JWH-018. Anal. Bioanal. Chem. 398(5), 2141-2153 (2010).
[4]. Chimalakonda, K.C., Moran, C.L., Kennedy, P.D., et al. Solid-phase extraction and quantitative measurement of omega and omega-1 metabolites of JWH-018 and JWH-073 in human urine. Anal. Chem. 83(16), 6381-6388 (2011)..