ADBICA N-pentanoic acid metabolite (Synonyms: ADB-PICA N-pentanoic acid metabolite)

ADBICA is a synthetic cannabinoid (CB) that has recently been identified in herbal blends [1]. Its name refers to its structure, which has a 1-amino-3,3-dimethyl-1-oxobutan-2-yl (ADB) group linked to a 1-pentyl-1H-indole-3-carboxamide (PINACA) base at the amide group. The base is similar to that of the aminoalkylindoles which potently activate both CB receptors.[2]  ADBICA N-pentanoic acid metabolite is a potential phase 1 metabolite of ADBICA, based on the known metabolism of similar compounds. The physiological and toxicological properties of this compound have not been determined. This product is intended for forensic and research applications.

Reference:
[1]. Uchiyama, N., Matsuda, S., Kawamura, M., et al. Two new-type cannabimimetic quinolinyl carboxylates, QUPIC and QUCHIC, two new cannabimimetic carboxamide derivatives, ADB-FUBINACA and ADBICA, and five synthetic cannabinoids detected with a thiophene derivative α-PVT and an opioid receptor agonist AH-7921 identified in illegal products. Forensic Toxicol. 31(2), 223-240 (2013).
[2]. Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding. Drug Alcohol Depend. 60(2), 133-140 (2000).