Ampreloxetine hydrochloride |
| Catalog No.GC70271 |
Ampreloxetine (TD-9855) hydrochloride is an orally active and CNS-penetrant inhibitor of Norepinephrine transporter (NET) and Serotonin 5-HT uptake transporter (SERT), but not Dopamine transporter (DAT).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1227056-87-2
Sample solution is provided at 25 µL, 10mM.
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Ampreloxetine (TD-9855) hydrochloride is an orally active and CNS-penetrant inhibitor of Norepinephrine transporter (NET) and Serotonin 5-HT uptake transporter (SERT), but not Dopamine transporter (DAT). Ampreloxetine hydrochloride binds norepinephrine transporters (NET) and serotonin transporters (SERT) with EC50 values of 11.7 ng/mL and 50.8 ng/mL, respectively, in plasma.
Ampreloxetine hydrochloride (0.3-60 mg/kg; PO; single dose) is irrespective between plasma concentration and dose level in rat model[1].
Review for Ampreloxetine hydrochloride
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for Ampreloxetine hydrochloride
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