Amylin (human) (amidated) (trifluoroacetate salt) (Synonyms: IAPP (human) (amidated), Islet Amyloid Polypeptide (human) (amidated)) |
Catalog No.GC42795 |
Amylin is a peptide hormone secreted from pancreatic β-cells that reduces food intake, decreases glucagon secretion, slows gastric emptying, and increases satiety.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
Amylin is a peptide hormone secreted from pancreatic β-cells that reduces food intake, decreases glucagon secretion, slows gastric emptying, and increases satiety. Native amylin is a cleavage product of proamylin that is processed and amidated at the C-terminus, a modification that is required for its biological activities. Amidated amylin increases the rate of glycogen synthesis induced by insulin in isolated rat soleus muscle when used at a concentration of 1 nM, while linear non-amidated amylin has no effect. Amylin is present in amyloid aggregates derived from the pancreatic islets of humans with type 2 diabetes and, in vitro, amidated amylin is more amyloidogenic than the free acid form. Amylin (human) (amidated) is a 37-residue amidated form of amylin that contains a disulfide bridge between cysteines two and seven.
Average Rating: 5
(Based on Reviews and 22 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *