Antalarmin |
| Catalog No.GC70559 |
Antalarmin is a selective nonpeptide corticotropin-releasing factor receptor 1 (CRHR1) antagonist with a Ki of 2.7 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 157284-96-3
Sample solution is provided at 25 µL, 10mM.
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Antalarmin inhibits the effect of corticotrophin-releasing factor (CRF) on Aβ1-42 levels through the cAMP/PKA signaling pathway[2].
Antalarmin (10 mg/kg; i.p.; daily for 4 weeks) leads to an improvement of chronic mild stress (CMS)-induced modifications in mice[1].
Antalarmin (20 mg/kg; i.p.; daily for 7 days) significantly reduces Aβ1-42 levels in sub-acute stressed Tg2576 mice[2].
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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