1,2,3,4,7,8,9-Heptachlorodibenzofuran |
| رقم الكتالوجGC90937 |
مركب الديوكسين المشابه للبولي كلوريد داي بنزوفوران
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 55673-89-7
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
1,2,3,4,7,8,9-Heptachlorodibenzofuran is a dioxin-like polychlorinated dibenzofuran (PCDF).1 It induces the expression of the genes encoding the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1B1, as well as the aryl drocarbon receptor repressor (AhRR) in primary human peripheral blood lymphocytes and increases ethoxyresorufin-O-deetlase (EROD) activity, a marker of CYP1A1 activity, in isolated human peripheral blood lymphocytes in a concentration-dependent manner. 1,2,3,4,7,8,9-Heptachlorodibenzofuran decreases the number of splenic plaque-forming cells, indicating immunosuppression, and increases hepatic microsomal aryl drocarbon droxylase (AHH) activity in mice induced with sheep red blood cells (ED50s = 12 and 700 nmol/kg, respectively).2 It has been found in human breastmilk and in the air near municipal waste incinerators.3,4
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *