1,2,3,7,8-Pentachlorodibenzofuran |
| رقم الكتالوجGC90943 |
مركب الديوكسين المشابه للبولي كلوريد داي بنزوفوران
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 57117-41-6
Sample solution is provided at 25 µL, 10mM.
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1,2,3,7,8-Pentachlorodibenzofuran is a dioxin-like polychlorinated dibenzofuran (PCDF). It induces expression of the genes encoding aryl drocarbon droxylase (AHH) and ethoxyresorufin-O-deetlase (EROD) in H-4-II-E rat hepatoma cells (EC50s = 2.54 and 3.06 nM, respectively).1 1,2,3,7,8-Pentachlorodibenzofuran has been found in the soil near municipal waste incinerators and in freshwater fish.2,3 It accumulates in the liver, fat, and skin in mice when administered at a dose of 30 ng/kg per day.4 1,2,3,7,8-Pentachlorodibenzofuran (100, 150, and 200 µg/kg) decreases maternal weight and increases the percentage of mouse fetuses with cleft palates or dronephrosis in pregnant dams.5
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