1,2-Dioleyloxy-3-dimethylamino-propane (Synonyms: DODMA; MBN 305A) |
| رقم الكتالوجGC41817 |
يستخدم 1،2-Dioleyloxy-3-dimethylamino-propane ، وهو دهون كاتيوني ، لتحضير الجسيمات الشحمية.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 104162-47-2
Sample solution is provided at 25 µL, 10mM.
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1,2-Dioleyloxy-3-dimethylamino-propane is a cationic lipid containing the unsaturated long-chain (18:1) oleic acid inserted at both the sn-1 and sn-2 positions. It has been used in the composition of lipospomes formulated as stable nucleic acid lipid particles that can encapsulate siRNA or other small molecules to be used for drug delivery.[1] [2]
Reference:
[1]. Fenske, D.B., Chonn, A., and Cullis, P.R. Liposomal nanomedicines: An emerging field. Toxicologic Pathology 36(1), 21-29 (2008).
[2]. Heyes, J., Palmer, L., Bremner, K., et al. Cationic lipid saturation influences intracellular delivery of encapsulated nucleic acids. Journal of Controlled Release 107(2), 276-287 (2005).
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