1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one |
رقم الكتالوجGC71928 |
1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one هو مثبط نوكليوكابسيد البروتين N القوي يمكن عزله من Curcuma kwangsiensis.
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Cas No.: 149732-52-5
Sample solution is provided at 25 µL, 10mM.
1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one is a potent nucleocapsid (N) protein inhibitor can be isolated from Curcuma kwangsiensis. 1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one exhibits excellent antiviral activity against HCoV-OC43 and SARS-CoV-2,with EC50 values of 0.16 μM and 0.17 μM, respectively.
References:
[1]. Yang Liu, et al. 1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one inhibits SARS-CoV-2 by targeting the nucleocapsid protein. Acta Materia Medica. 2023. Vol. 2(3):270-280.
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