17β-HSD10-IN-1 |
| رقم الكتالوجGC71338 |
17β-HSD10-IN-1 (المركب 9) هو مثبط نشط عن طريق الفم لـ 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10) مع نفاذية الدم والدماغ.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2316765-78-1
Sample solution is provided at 25 µL, 10mM.
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17β-HSD10-IN-1 (compound 9) is an orally active inhibitor of 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10) with blood-brain permeability. 17β-HSD10-IN-1 doesn't result additional effects for mitochondrial off-targets and cytotoxic or neurotoxic effects.
References:
[1]. Benek O, et al. Development of submicromolar 17尾-HSD10 inhibitors and their in vitro and in vivo evaluation. Eur J Med Chem. 2023 Oct 5;258:115593.聽
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