17-phenyl trinor Prostaglandin F2α methyl ester (Synonyms: Bimatoprost methyl ester, 17phenyl trinor PGF2α methyl ester) |
رقم الكتالوجGC40392 |
17-فينيل ترينور بروستاغلاندين F2α ؛ إستر الميثيل هو دواء أولي لـ Bimatoprost.
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Cas No.: 38315-47-8
Sample solution is provided at 25 µL, 10mM.
Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. 17-phenyl trinor PGF2α methyl ester is a lipophilic analog of 17-phenyl trinor PGF2α, a potent agonist for the FP receptor. 17-phenyl trinor PGF2α binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α. Esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.
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