18β-Glycyrrhetyl-3-O-sulfate |
رقم الكتالوجGC71042 |
18β-Glycyrrhetyl-3-O-sulfate (حمض Glycyrrhetic 3-O (كبريتات الهيدروجين)) هو نوع فعال من 2 11β-hydroxysteroid dehydrogenase (11β-HSD2) مع IC50 من 0.10 µM باستخدام ميكروسوم الكلى الفئران.
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Cas No.: 10251-38-4
Sample solution is provided at 25 µL, 10mM.
18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)) is a potent type 2 11β-hydroxysteroid dehydrogenase (11β-HSD2) inhibitor with an IC50 of 0.10 µM using rat kidney microsome. 18β-Glycyrrhetyl-3-O-sulfate is the major metabolite of Glycyrrhetinic acid (GA). 18β-Glycyrrhetyl-3-O-sulfate is the substrate of organic anion transporter (OAT) 1 and OAT3. 18β-Glycyrrhetyl-3-O-sulfate has anti-inflammatory effects and has the potential for pseudohyperaldosteronism research.
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