2'-Deoxyadenosine-5'-O-diphosphoribose (sodium salt) |
| رقم الكتالوجGC90791 |
محفز TRPM2
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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2'-Deoxyadenosine-5'-O-diphosphoribose is a transient receptor potential melastatin 2 (TRPM2) agonist.1 It increases calcium-induced currents in an inside-out patch clamp assay using HEK293 cells expressing human TRPM2 when used at a concentration of 30 µM. 2'-Deoxyadenosine-5'-O-diphosphoribose has been found in Jurkat cells. It is also a substrate of nucleotide triphosphate diphosphatase 9 (NUDT9), a mitochondrial enzyme involved in drolyzing pyrophosphates.2
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