4-(3,4-Difluorobenzo)curcumin |
رقم الكتالوجGC91135 |
مركب الكومارين شبه الصناعي ذو الفعالية المضادة للطفيليات والسرطان.
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Cas No.: 1170354-22-9
Sample solution is provided at 25 µL, 10mM.
4-(3,4-Difluorobenzo)curcumin (CDF) is a semisynthetic coumarin with antiparasitic and anticancer activities.1,2 It reduces the number of Vero cells infected with T. gondii promastigotes and amastigotes (EC50s = 0.8 and 0.37 µM, respectively).1 CDF (4 and 8 µM) enhances 5-fluorouracil- and oxaliplatin-induced inhibition of primary and secondary colonosphere formation by chemoresistant HCT116 cells.2
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