80-O18 |
| رقم الكتالوجGC91541 |
80-O18 is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for use in vitro.
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Cas No.: 1638334-27-6
Sample solution is provided at 25 µL, 10mM.
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80-O18 is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for use in vitro.[1] An LNP complex containing 80-O18 and a Cre-GFP fusion protein tagged with one of three assay-specific chloroalkane tags displays high total cellular uptake and functional delivery in reporter assays using HeLa-DsRed cells, as well as cytosolic delivery in a chloroalkane penetration assay (CAPA) screen using HeLa-HGM cells.
References:
[1].Wang, J., Zhang, S., Li, Y., et al.Investigating the cytosolic delivery of proteins by lipid nanoparticles using the chloroalkane penetration assayBiochemistry(2024).
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