ABM-14 |
رقم الكتالوجGC62391 |
ABM-14 عبارة عن يجند لاستهداف مستقبلات الأندروجين (AR) لبروتاكيرتبط ABM-14 برابطة لـ VHL عبر رابط لتشكيل ARCC-4 لتقليل AR
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Cas No.: 1973408-76-2
Sample solution is provided at 25 µL, 10mM.
ABM-14 is a ligand for targeting androgen receptor (AR) for PROTAC. ABM-14 binds to a ligand for VHL via linker to form ARCC-4 to degrade AR[1].
[1]. Meizhong Jin, et al. Compounds and methods for the targeted degradation of the androgen receptor. WO2016118666A1.
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