الصفحة الرئيسية>>ADAMTS-5-IN-2

ADAMTS-5-IN-2

رقم الكتالوجGC70743

ADAMTS-5-IN-2 (مركب 25) هو مثبط قوي ADAMTS-5 مع قيمة IC50 من 0.71 µM.

Products are for research use only. Not for human use. We do not sell to patients.

ADAMTS-5-IN-2 التركيب الكيميائي

Cas No.: 294648-66-1

الحجم السعر المخزون الكميّة
10mM (in 1mL DMSO)
221٫00
متوفر
1 mg
162٫00
متوفر
5 mg
324٫00
متوفر
10 mg
486٫00
متوفر

Tel:(909) 407-4943 Email: sales@glpbio.com

مراجعات العميل

بناء على آراء العملاء.

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

    Bioactive Compounds Premium Provider

Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
ADAMTS-5-IN-2 (compound 25) is a potent ADAMTS-5 inhibitor with an IC50 value of 0.71 µM. ADAMTS-5-IN-2 has the potential for the research of modifying osteoarthritis.

References:
[1]. Bompiani KM, et al. High-Throughput Screening Uncovers Novel Botulinum Neurotoxin Inhibitor Chemotypes. ACS Comb Sci. 2016 Aug 8;18(8):461-74.
[2]. Matthew G. Bursavich; et al. 5′-Phenyl-3′H-spiro[indoline-3,2′-[1,3,4]thiadiazol]-2-one inhibitors of ADAMTS-5 (Aggrecanase-2). Bioorganic & Medicinal Chemistry Letters. 2007, 17(20), 5630-5633.

مراجعات

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