الصفحة الرئيسية>>Signaling Pathways>> PROTAC>>Aminooxy-PEG3-bromide hydrochloride

Aminooxy-PEG3-bromide hydrochloride

رقم الكتالوجGC64797

Aminooxy-PEG3-bromide hydrochloride عبارة عن رابط PROTAC قائم على PEG يمكن استخدامه في تخليق PROTACs

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Aminooxy-PEG3-bromide hydrochloride التركيب الكيميائي

الحجم السعر المخزون الكميّة
25 mg
495٫00
متوفر
50 mg
855٫00
متوفر
100 mg
1350٫00
متوفر

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مراجعات العميل

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  • GlpBio Citations

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Aminooxy-PEG3-bromide (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

مراجعات

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