AP1189 acetate (Synonyms: AP-1189; AP 1189; AP1189; AP1189 acetate;) |
| رقم الكتالوجGB62274 |
AP1189 is a biased agonist at receptors MC1 and MC3.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 959850-74-9
Sample solution is provided at 25 µL, 10mM.
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AP1189 is a biased agonist at receptors MC1 and MC3. AP1189 reduced cytokine release, an effect reliant on both MC1 and MC3 as evident from the use of Mc1r(-/-) and Mc3r(-/-) macrophages. No melanogenesis was induced by AP1189 in B16-F10 melanocytes. In vivo, oral AP1189 elicited anti-inflammatory actions in peritonitis and, upon administration at the peak of inflammation, accelerated the resolution phase by ∼3-fold.
Review for AP1189 acetate
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for AP1189 acetate
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