APPA |
| رقم الكتالوجGB40100 |
APPA is an aldose reductase inhibitor with an IC50 value of 0.0223 μM. APPA could inhibit apoptosis in rat glomerular mesangial cells in vitro. In addition, APPA improved the pathological symptoms of streptozotocin-induced diabetic nephropathy (DN) in rats by affecting antioxidant activities and reducing the levels of TGF-β, collagen IV, and laminin.
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Cas No.: 100750-39-8
Sample solution is provided at 25 µL, 10mM.
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APPA is an aldose reductase inhibitor with an IC50 value of 0.0223 μM. APPA could inhibit apoptosis in rat glomerular mesangial cells in vitro. In addition, APPA improved the pathological symptoms of streptozotocin-induced diabetic nephropathy (DN) in rats by affecting antioxidant activities and reducing the levels of TGF-β, collagen IV, and laminin.
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