Artilide fumarate (Synonyms: Artilide fumarate; U 88943E; U88943E; U-88943E) |
| رقم الكتالوجGB62288 |
Artilide, also known as U88943 or U88943E, is a drug used for the treatment of cardiac arrhythmias.
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Cas No.: 133267-20-6
Sample solution is provided at 25 µL, 10mM.
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Artilide, also known as U88943 or U88943E, is a drug used for the treatment of cardiac arrhythmias. Artilide is a class III antiarrhythmic which is structurally-related to ibutilide and d,l-sotalol. Artilide had demonstrated inducibe ventricular arrhythmias prior to treatment. This antiarrhythmic action was associated with significant increases in ventricular refractoriness and monophasic action potential duration. Lower doses of artilide tended to reduce the incidence of spontaneous ventricular arrhythmias but these effects were not significant. These results are consistent with the concept that spontaneous and pacing induced ventricular arrhythmias result from different mechanisms, and that class III anti-arrhythmic agents are more effective in suppressing induced ventricular tachycardia due to reentry than spontaneous arrhythmias which result from nonreentrant mechanisms.
Review for Artilide fumarate
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for Artilide fumarate
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