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Atovaquone D4

رقم الكتالوجGC38889

Atovaquone D4 هو الديوتيريوم المسمى Atovaquone.

Products are for research use only. Not for human use. We do not sell to patients.

Atovaquone D4 التركيب الكيميائي

Cas No.: 2070015-14-2

الحجم السعر المخزون الكميّة
1mg
324٫00
متوفر
5mg
1020٫00
متوفر

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مراجعات العميل

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  • GlpBio Citations

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  • Bioactive Compounds Premium Provider

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Sample solution is provided at 25 µL, 10mM.

Description of Atovaquone D4

Atovaquone D4 is the deuterium labeled Atovaquone. Atovaquone is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia[1].

[1]. Looareesuwan, S., et al., Clinical studies of atovaquone, alone or in combination with other antimalarial drugs, for treatment of acute uncomplicated malaria in Thailand. Am J Trop Med Hyg, 1996. 54(1): p. 62-6.

Chemical Properties of Atovaquone D4

Cas No. 2070015-14-2 SDF
Canonical SMILES O=C1C2=C(C(C(O)=C1[C@@H]3CC[C@@H](C4=CC=C(Cl)C=C4)CC3)=O)C([2H])=C([2H])C([2H])=C2[2H]
Formula C22H15D4ClO3 M.Wt 370.86
الذوبان Chloroform: soluble Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Atovaquone D4

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.6964 mL 13.4822 mL 26.9644 mL
5 mM 0.5393 mL 2.6964 mL 5.3929 mL
10 mM 0.2696 mL 1.3482 mL 2.6964 mL
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In vivo Formulation Calculator (Clear solution) of Atovaquone D4

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for Atovaquone D4

Average Rating: 5 ★★★★★ (Based on Reviews and 31 reference(s) in Google Scholar.)

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