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Atuzabrutinib

رقم الكتالوجGC70685

Atuzabrutinib (SAR 444727) هو مثبط انتقائي قابل للعكس لمثبط Btk (بروتون التيروزين كيناز).

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Atuzabrutinib التركيب الكيميائي

Cas No.: 1581714-49-9

الحجم السعر المخزون الكميّة
10mM (in 1mL DMSO)
620٫00
متوفر
1 mg
207٫00
متوفر
5 mg
522٫00
متوفر
10 mg
882٫00
متوفر

Tel:(909) 407-4943 Email: sales@glpbio.com

مراجعات العميل

بناء على آراء العملاء.

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

    Bioactive Compounds Premium Provider

Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Atuzabrutinib (SAR 444727) is a potent, selective reversible inhibitor of Btk (Bruton's tyrosine kinase) inhibitor. Atuzabrutinib inhibits neutrophil recruitment via inhibition of macrophage antigen-1 signalling.

PRN473 (20 mg/kg) significantly reduces intravascular crawling and neutrophil recruitment into inflamed tissue in a model of sterile liver injury, down to levels seen in Btk-deficient animals[1].

مراجعات

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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