AVE5688 |
| رقم الكتالوجGC31627 |
AVE5688 هو مثبط للجليكوجين فسفوريلاز (GP) ، مع IC50s من 430 نانومتر و 915 نانومتر و Kds من 170 نانومتر و 530 نانومتر لفوسفوريلاز الجليكوجين في الأرانب (rmGPb و rmGPa ، على التوالي) ؛ يمكن استخدام AVE5688 في البحث عن مرض السكري من النوع 2
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 613260-13-2
Sample solution is provided at 25 µL, 10mM.
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AVE5688 is an inhibitor of glycogen phosphorylase (GP), with IC50s of 430 nM and 915 nM and Kds of 170 nM and 530 nM for rabbit muscle glycogen phosphorylase (rmGPb and rmGPa, respectively); AVE5688 can be used for the research of type 2 diabetes.
AVE5688 is an inhibitor of glycogen phosphorylase (GP), with IC50s of 430 nM and 915 nM and Kds of 170 nM and 530 nM for rabbit muscle glycogen phosphorylase (rmGPb and rmGPa, respectively)[1].
[1]. Anderka O, et al. Thermodynamic characterization of allosteric glycogen phosphorylase inhibitors. Biochemistry. 2008 Apr 22;47(16):4683-91.
Average Rating: 5 (Based on Reviews and 36 reference(s) in Google Scholar.)
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