β-Amanitin |
| رقم الكتالوجGC19807 |
β؛ -Amanitin عبارة عن سم ببتيد دوري في فطر Amanita phalloides السام. β ؛ - يمنع أمانيتين حقيقيات النوى بوليميريز الحمض النووي الريبي الثاني والثالث. β ؛ -أمنيتين يثبط تخليق البروتين. β ؛ -يمكن استخدام أمنيتين كمكون سام للخلايا في اتحادات الأجسام المضادة والأدوية (ADCs).
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Cas No.: 21150-22-1
Sample solution is provided at 25 µL, 10mM.
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β-Amanitin is a cyclic peptide found in several species of the Amanita genus, as well as other poisonous fungi.1 It inhibits RNA polymerase II and III but not RNA polymerase I or bacterial RNA polymerase, thus preventing mammalian protein synthesis.2,3 The biological activity of this toxin is similar to that of α-amanitin but differs structurally by the presence of a carboxyl group, which is useful for coupling reactions.4
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