الصفحة الرئيسية>>Analytical Standards>>BB-22 3-carboxyindole metabolite

BB-22 3-carboxyindole metabolite

رقم الكتالوجGC42899

BB-22 is an analog of the potent synthetic cannabinoid, JWH 018 that is structurally similar to PB-22 and its derivative, 5-fluoro PB-22.

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BB-22 3-carboxyindole metabolite التركيب الكيميائي

Cas No.: 858515-71-6

الحجم السعر المخزون الكميّة
1mg
163٫00
متوفر
5mg
385٫00
متوفر
10mg
599٫00
متوفر

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Sample solution is provided at 25 µL, 10mM.

Description of BB-22 3-carboxyindole metabolite

BB-22 is an analog of the potent synthetic cannabinoid, JWH 018 that is structurally similar to PB-22 and its derivative, 5-fluoro PB-22 . [1] [2]  Both BB-22 and PB-22 are distinctive in that an 8-hydroxyquinoline replaces the naphthalene group of JWH 018. BB-22 3-carboxyindole metabolite is expected to be a metabolite of BB-22 that would be detectable both in serum and urine. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.

Reference:
[1]. Sobolevsky, T., Prasolov, I., and Rodchenkov, G. Detection of JWH-018 metabolites in smoking mixture post-administration urine. Forensic Sci. Int. 200(1-3), 141-147 (2010).
[2]. Moran, C.L., Le, V.H., Chimalakonda, K.C., et al. Quantitative measurement of JWH-018 and JWH-073 metabolites excreted in human urine. Anal. Chem. 83(11), 4228-4236 (2011).

Chemical Properties of BB-22 3-carboxyindole metabolite

Cas No. 858515-71-6 SDF
Chemical Name 1-(cyclohexylmethyl)-1H-indole-3-carboxylic acid
Canonical SMILES O=C(O)C1=CN(CC2CCCCC2)C3=C1C=CC=C3
Formula C16H19NO2 M.Wt 257.3
الذوبان DMF: 2 mg/ml,DMSO: 2.5 mg/ml,Ethanol: 3.3 mg/ml,Ethanol:PBS(pH 7.2) (1:1): 0.50 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of BB-22 3-carboxyindole metabolite

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.8865 mL 19.4326 mL 38.8651 mL
5 mM 0.7773 mL 3.8865 mL 7.773 mL
10 mM 0.3887 mL 1.9433 mL 3.8865 mL
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In vivo Formulation Calculator (Clear solution) of BB-22 3-carboxyindole metabolite

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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