bio-THZ1 |
| رقم الكتالوجGC62653 |
bio-THZ1 هو نسخة معالجة بيوتينيلات من THZ1 وترتبط بشكل لا رجعة فيه بـ CDK7THZ1 هو مثبط CDK7 انتقائي وفعال مع IC50 من 3.2 نانومتر
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1604811-14-4
Sample solution is provided at 25 µL, 10mM.
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bio-THZ1 is a biotinylated version of THZ1 and binds irreversibly to CDK7. THZ1 is a selective and potent covalent CDK7 inhibitor with an IC50 of 3.2 nM[1].
[1]. Kwiatkowski N, et al. Targeting transcription regulation in cancer with a covalent CDK7 inhibitor. Nature. 2014 Jul 31;511(7511):616-20.
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