Bis-propargyl-PEG4 |
| رقم الكتالوجGC63408 |
Bis-propargyl-PEG4 عبارة عن رابط PROTAC قائم على PEG يُستخدم في تركيب PROTACs
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 159428-42-9
Sample solution is provided at 25 µL, 10mM.
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Bis-propargyl-PEG4 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG4 is used for the synthesis of demethylvancomycin dimers[1][2].
Bis-propargyl-PEG4 can be used in the synthesis of demethylvancomycin dimers against vancomycin-resistant enterococcus faecalis[2].
[1]. Pearlie BURNETTE, et al. Dimeric immuno-modulatory compounds against cereblon-based mechanisms. WO2020014489A2.
[2]. Jiang, et al. Design, synthesis and biological activity of novel demethylvancomycin dimers against vancomycin-resistant enterococcus faecalis. Tetrahedron, 2018: 74(27), 3527-3533.
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