Bis-propargyl-PEG8 |
رقم الكتالوجGC67179 |
Bis-propargyl-PEG8 (المركب 16e) عبارة عن رابط PROTAC قائم على PEG يمكن استخدامه في تركيب PROTACs.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1092554-87-4
Sample solution is provided at 25 µL, 10mM.
Bis-propargyl-PEG8 (compound 16e) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. Jervis PJ, et al. Towards multivalent CD1d ligands: synthesis and biological activity of homodimeric α-galactosyl ceramide analogues. Carbohydr Res. 2012 Jul 15;356:152-62.
Average Rating: 5
(Based on Reviews and 30 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *