Bis-propargyl-PEG8 |
| رقم الكتالوجGC67179 |
Bis-propargyl-PEG8 (المركب 16e) عبارة عن رابط PROTAC قائم على PEG يمكن استخدامه في تركيب PROTACs.
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Cas No.: 1092554-87-4
Sample solution is provided at 25 µL, 10mM.
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Bis-propargyl-PEG8 (compound 16e) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. Jervis PJ, et al. Towards multivalent CD1d ligands: synthesis and biological activity of homodimeric α-galactosyl ceramide analogues. Carbohydr Res. 2012 Jul 15;356:152-62.
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