Casein kinase 1δ-IN-6 |
رقم الكتالوجGC71277 |
Casein kinase 1δ-IN-6 هو مثبط كيناز البروتين الفعال والانتقائي CK-1δ مع IC50 من 23 نانومتر.
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Cas No.: 1579991-01-7
Sample solution is provided at 25 µL, 10mM.
Casein kinase 1δ-IN-6 is a potent and selective protein kinase CK-1δ inhibitor with an IC50 of 23 nM. Casein kinase 1δ-IN-6 shows neuroprotective and anti-inflammatory properties both in vitro and in vivo. Casein kinase 1δ-IN-6 is a promising drug candidate and can be used for neurodegenerative diseases research.
References:
[1]. José A Morales-Garcia, et al. Biological and Pharmacological Characterization of Benzothiazole-Based CK-1δ Inhibitors in Models of Parkinson's Disease. ACS Omega. 2017 Aug 31;2(8):5215-5220.
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