Desethyl Hydroxychloroquine (Synonyms: Cletoquine ) |
| رقم الكتالوجGC47192 |
ديسيثيل هيدروكسي كلوروكوين (ديسيثيل هيدروكسي كلوروكوين) هو مستقلب رئيسي نشط لهيدروكسي كلوروكوين.
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Cas No.: 4298-15-1
Sample solution is provided at 25 µL, 10mM.
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Desethyl hydroxychloroquine is an active metabolite of hydroxychloroquine .1 It is formed via the desethylation of hydroxychloroquine in the liver, a process mediated by the cytochrome P450 (CYP) isoforms CYP2D6, CYP3A4, CYP3A5, and CYP2C8.
1.Charlier, B., Pingeon, M., Dal Piaz, F., et al.Development of a novel ion-pairing HPLC-FL method for the separation and quantification of hydroxychloroquine and its metabolites in whole bloodBiomed. Chromatogr.32(8)e4258(2018)
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