CCR4 antagonist 3-1 |
| رقم الكتالوجGC70999 |
CCR4 antagonist 3-1 هو مضاد قوي لمستقبلات الكيموكين 4 (CCR4) بقيمة IC50 قدرها 1.7 ميكرومتر لـ TARC (الغدة الزعترية وتفعيل الكيموكين الخاضع للتنظيم).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1957-01-3
Sample solution is provided at 25 µL, 10mM.
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CCR4 antagonist 3 (compound 1) (0.5 mg/kg for IV; 2 mg/kg for PO; single dosage) exhibits a high clearance, short half-life and low oral bioavailability[1].
References:
[1]. Wang X, et al. Optimization of 2-aminothiazole derivatives as CCR4 antagonists. Bioorg Med Chem Lett. 2006 May 15;16(10):2800-3.
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