CD33 splicing modulator 1 |
| رقم الكتالوجGC70896 |
CD33 splicing modulator 1 (المركب 1) هو مُعدل ربط CD33.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2762547-05-5
Sample solution is provided at 25 µL, 10mM.
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CD33 splicing modulator 1 (Compound 1) is a CD33 splicing modulator. CD33/Siglec 3 is a myeloid lineage cell surface receptor that is known to regulate microglia activity. CD33 splicing modulator 1 increases exon 2 skipping in cellular mRNA pools. CD33 splicing modulator 1 has the potential for the research of neurodegenerative disease including Alzheimer's disease.
References:
[1]. Chappie TA, et al. Discovery of Small-Molecule CD33 Pre-mRNA Splicing Modulators. ACS Med Chem Lett. 2022;13(1):55-62.
Review for CD33 splicing modulator 1
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for CD33 splicing modulator 1
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