cRIPGBM |
رقم الكتالوجGC34543 |
cRIPGBM ، مشتق استباقي لـ RIPGBM ، محفز انتقائي من نوع الخلية للاستماتة في الخلايا الجذعية السرطانية GBM (CSCs) عن طريق الارتباط ببروتين كيناز 2 المتفاعل مع المستقبلات (RIPK2) ، مع EC50 من 68 نانومتر في خلايا GBM-1
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Cas No.: 2361988-76-1
Sample solution is provided at 25 µL, 10mM.
cRIPGBM, a proapoptotic derivative of RIPGBM, a cell type-selective inducer of apoptosis in GBM cancer stem cells (CSCs) by binding to receptor-interacting protein kinase 2 (RIPK2), with an EC50 of 68 nM in GBM-1 cells[1]. RIPK2[1].
[1]. Lucki NC, et al. A cell type-selective apoptosis-inducing small molecule for the treatment of brain cancer. Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6435-6440.
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