D-3263 hydrochloride |
رقم الكتالوجGC32961 |
هيدروكلوريد D-3263 عبارة عن ناهض TRPM8 مغلف معويًا ومتاحًا بيولوجيًا عن طريق الفم (مستقبلات عابرة محتملة لعضو الميلستاتين 8)
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Cas No.: 1008763-54-9
Sample solution is provided at 25 µL, 10mM.
D-3263 hydrochloride is an enteric-coated, orally bioavailable (transient receptor potential melastatin member 8) TRPM8 agonist.
D-3263 hydrochloride binds to and activates TRPM8, which may result in an increase in calcium and sodium entry; the disruption of calcium and sodium homeostasis; and the induction of cell death in TRPM8-expressing tumor cells. D-3263 hydrochloride may decrease dihydrotestosterone (DHT) levels, which may contribute to its inhibitory effects on prostate cancer and BPH[1].
[1]. enteric-coated TRPM8 agonist D-3263 hydrochloride
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