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D-3263 hydrochloride

رقم الكتالوجGC32961

هيدروكلوريد D-3263 عبارة عن ناهض TRPM8 مغلف معويًا ومتاحًا بيولوجيًا عن طريق الفم (مستقبلات عابرة محتملة لعضو الميلستاتين 8)

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D-3263 hydrochloride التركيب الكيميائي

Cas No.: 1008763-54-9

الحجم السعر المخزون الكميّة
10mM (in 1mL DMSO)
232٫00
متوفر
1mg
110٫00
متوفر
5mg
258٫00
متوفر
10mg
405٫00
متوفر
50mg
1195٫00
متوفر
100mg
1930٫00
متوفر

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مراجعات العميل

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

D-3263 hydrochloride is an enteric-coated, orally bioavailable (transient receptor potential melastatin member 8) TRPM8 agonist.

D-3263 hydrochloride binds to and activates TRPM8, which may result in an increase in calcium and sodium entry; the disruption of calcium and sodium homeostasis; and the induction of cell death in TRPM8-expressing tumor cells. D-3263 hydrochloride may decrease dihydrotestosterone (DHT) levels, which may contribute to its inhibitory effects on prostate cancer and BPH[1].

[1]. enteric-coated TRPM8 agonist D-3263 hydrochloride

مراجعات

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