الصفحة الرئيسية>>Signaling Pathways>> Apoptosis>>[D-Leu-4]-OB3

[D-Leu-4]-OB3

رقم الكتالوجGC72183

تمنع [D-Leu-4]-OB3 التعبير عن الجينات المؤيدة للالتهابات والتكاثر والانبثاث والتعبير PD-L1.

Products are for research use only. Not for human use. We do not sell to patients.

[D-Leu-4]-OB3 التركيب الكيميائي

Cas No.: 289056-32-2

الحجم السعر المخزون الكميّة
5 mg
45٫00
متوفر
10 mg
63٫00
متوفر
25 mg
124٫00
متوفر
50 mg
198٫00
متوفر
100 mg
315٫00
متوفر

Tel:(909) 407-4943 Email: sales@glpbio.com


مراجعات العميل

بناء على آراء العملاء.

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

    Bioactive Compounds Premium Provider

Sample solution is provided at 25 µL, 10mM.

Description of [D-Leu-4]-OB3

[D-Leu-4]-OB3 inhibits expressions of pro-inflammatory, proliferative and metastatic genes andPD-L1expression. [D-Leu-4]-OB3 stimulates expression of pro-apoptotic genes.

References:
[1]. Yih Ho,et al. Leptin-derived peptides block leptin-induced proliferation by reducing expression of pro-inflammatory genes in hepatocellular carcinoma cells.Food Chem Toxicol.2019 Nov;133:110808.

Chemical Properties of [D-Leu-4]-OB3

Cas No. 289056-32-2 SDF
Formula C29H50N8O12S M.Wt 734.82
الذوبان DMSO : 50 mg/mL (68.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) Storage Sealed storage, away from moisture
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of [D-Leu-4]-OB3

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.3609 mL 6.8044 mL 13.6088 mL
5 mM 0.2722 mL 1.3609 mL 2.7218 mL
10 mM 0.1361 mL 0.6804 mL 1.3609 mL
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In vivo Formulation Calculator (Clear solution) of [D-Leu-4]-OB3

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for [D-Leu-4]-OB3

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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