endo-BCN-PEG4-Val-Cit-PAB-MMAE |
| رقم الكتالوجGC62468 |
إن endo-BCN-PEG4-Val-Cit-PAB-MMAE عبارة عن رابط PEG ADC قابل للكسر مكون من 4 وحدات يستخدم في تركيب اقترانات الأجسام المضادة والأدوية (ADCs)
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Cas No.: 2762519-08-2
Sample solution is provided at 25 µL, 10mM.
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endo-BCN-PEG4-Val-Cit-PAB-MMAE is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
Average Rating: 5 (Based on Reviews and 16 reference(s) in Google Scholar.)
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