ERRα antagonist-1 |
| رقم الكتالوجGC38777 |
ERRα ؛ المضاد -1 (المركب أ) هو مضاد انتقائي ومستقبل ذو صلة عالية بهرمون الاستروجين α (ERRα). ERRα ؛ يمنع المضاد -1 تفاعل ERRα مع المستقبل المنشط بالبروليفورتر γ Coactivator-1α (PGC-1α) و PGC-1β ، قيم IC هي 170 نانومتر و 180 نانومتر ، على التوالي. ERRα ؛ المضاد -1 لا يمنع تفاعل أي من ERRβ أو ERRγ مع PGC-1α و PGC-1β coactivator ، كما أنه لا يمنع تفاعل ERα أو ERβ مع PGC-1α أو SRC-1.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1072145-33-5
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
ERRα antagonist-1 (Compound A) is a selective and high affinity estrogen-related receptor α (ERRα) antagonist. ERRα antagonist-1 inhibits interaction of ERRα with Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β, the IC50 values are 170 nM and 180 nM, respectively. ERRα antagonist-1 does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1[1].
[1]. Michael J. Chisamore, et al. Identification of Small Molecule Estrogen-Related
Average Rating: 5 (Based on Reviews and 4 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *