الصفحة الرئيسية>>Signaling Pathways>> PROTAC>>Folate-PEG3-NHS ester

Folate-PEG3-NHS ester

رقم الكتالوجGC64313

Folate-PEG3-NHS ester عبارة عن رابط PROTAC قائم على PEG يمكن استخدامه في تخليق PROTACs

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Folate-PEG3-NHS ester التركيب الكيميائي

الحجم السعر المخزون الكميّة
25 mg
702٫00
متوفر
50 mg
1134٫00
متوفر

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مراجعات العميل

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  • GlpBio Citations

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  • Bioactive Compounds Premium Provider

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Folate-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

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