Atreleuton (Synonyms: A-85761.0, ABT-761, VIA-2291) |
رقم الكتالوجGC35425 |
Atreleuton (ABT-761) هو مثبط انتقائي وقابل للعكس ومتوفر بيولوجيًا 5-Lipoxygenase (5-LO).
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Cas No.: 154355-76-7
Sample solution is provided at 25 µL, 10mM.
Atreleuton (ABT-761) is a selective, reversible, and orally bioavailable 5-Lipoxygenase (5-LO) inhibitor. Atreleuton (ABT-761) exhibits potent and selective inhibition of leukotriene formation[1][2][3]. 5-LO[1]
[1]. VIA Pharmaceuticals Meets With FDA to Discuss Next Steps For VIA-2291 and Phase 3 Outcome Trial in Cardiovascular Disease. VIA Pharmaceuticals, Inc. [2]. Reid JJ, et al. ABT-761 (Abbott). Curr Opin Investig Drugs. 2001 Jan;2(1):68-71. [3]. Bell RL, et al. ABT-761 attenuates bronchoconstriction and pulmonary inflammation in rodents. J Pharmacol Exp Ther. 1997 Mar;280(3):1366-73.
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