CLIP 86-100 |
| رقم الكتالوجGC35708 |
CLIP 86-100 عبارة عن أحماض أمينية من 86 إلى 100 جزء من ببتيد السلسلة الثابتة المرتبط بالفئة الثانية (CLIP).
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Cas No.: 648881-58-7
Sample solution is provided at 25 µL, 10mM.
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CLIP (86-100) is amino acids 86 to 100 fragment of class II-associated invariant chain peptide (CLIP). CLIP is a small self-peptide and cleavage product of the invariant chain that resides in the HLA-II antigen binding groove and is believed to play a critical role in the assembly and transport of MHC class II alphabetaIi complexes through its interaction with the class II peptide-binding site[1].
[1]. van Luijn MM, et al. Class II-associated invariant chain peptide as predictive immune marker in minimal residual disease in acute myeloid leukemia. Oncoimmunology. 2015 Jan 7;3(12):e941737. eCollection 2014 Dec. [2]. Thayer WP, et al. Class II-associated invariant chain peptide-independent binding of invariant chain to class II MHC molecules. J Immunol. 1999 Feb 1;162(3):1502-9.
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