E3 ligase Ligand 10 |
رقم الكتالوجGC35924 |
E3 ligase Ligand 10 عبارة عن يجند لـ E3 ubiquitin ligaseيمكن توصيل E3 ligase Ligand 10 بالرابط الخاص بالبروتين عن طريق رابط لتكوين PROTACsPROTACs هي محرضات على تحلل البروتينات المعززة للسرطان بوساطة الانتشار
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Cas No.: 1073560-68-5
Sample solution is provided at 25 µL, 10mM.
E3 ligase Ligand 10 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 10 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
[1]. Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.
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