HCH6-1 |
رقم الكتالوجGC36212 |
HCH6-1 هو مضاد ثنائي الببتيد قوي وتنافسي لمستقبلات الببتيد Formyl 1 (FPR1)
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Cas No.: 1435265-06-7
Sample solution is provided at 25 µL, 10mM.
HCH6-1 is a competitive antagonist of Formyl peptide receptor 1 (FPR1), an emerging therapeutic target for the discovery of drugs to treat neutrophilic inflammatory diseases. HCH6-1 is a selective FPR1 inhibitor and has protective effects against acute lung injury (ALI). HCH6-1 inhibits superoxide anion generation, elastase release, and chemotaxis in human neutrophils activated by fMLF (an FPR1 agonist).
[1]. Yang SC, et al. Dipeptide HCH6-1 inhibits neutrophil activation and protects against acute lung injury by blocking FPR1. Free Radic Biol Med. 2017 May;106:254-269
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