N6-(4-Hydroxybenzyl)adenosine |
| رقم الكتالوجGC36680 |
N6- (4-Hydroxybenzyl) الأدينوزين هو مثبط لتراكم الصفائح الدموية الناتج عن الكولاجين في المختبر وقد تم عرض نطاق نشاطهم (IC50: 6.77-141 ميكرومتر)
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 110505-75-4
Sample solution is provided at 25 µL, 10mM.
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N6-(4-Hydroxybenzyl)adenosine is a inhibitor of platelet aggregation induced in vitro by collagen and their activity range was demonstrated (IC50: 6.77-141 μM). IC50 value: 6.77-141 μMTarget: P2Y12receptorAnti-aggregation activity of N6-(4-Hydroxybenzyl)adenosine could involve an interaction with the P2Y12receptor binding site.
[1]. Vistoli G, et al. Naturally occurring N(6)-substituted adenosines (cytokinin ribosides) are in vitro inhibitors of platelet aggregation: an in silico evaluation of their interaction with the P2Y(12) receptor. Bioorg Med Chem Lett. 2014 Dec 15;24(24):5652-5655.
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